Triamcinolone is an oral, intermediate-acting oral synthetic glucocorticoid, by inhalation, or as a topical ointment or cream.
Video Triamcinolone
Usage
Triamcinolone is used to treat a number of different medical conditions, such as eczema, lichen sclerosus, psoriasis, arthritis, allergies, ulcerative colitis, lupus, sympathetic ophthalmia, temporal arteritis, uveitis, inflammation of the eyes, keloid, urushiol-induced contact dermatitis, aphthous ulcers as triamcinolone acetonide), visualization during vitrectomy and prevention of asthma attacks. It will not cure asthma attacks once they start. It has also been used off-label for macular degeneration.
Before 2007 it was sold under the name Azmacort as a corticosteroid inhaler for long-term asthma treatment.
In 2010, TEVA and Perrigo launched the first generic inhalation triamcinolone.
Triamcinolone is used to alleviate eczema infection in fungal skin infections in combination of the drug econazole/triamcinolone.
The triamcinolone acetonide derivative is one of the Ledermix ingredients, the lotion (root canal) of lotion used between sessions, and Sanofi sells it under the brand name Nasacort. Triamcinolone acetonide is also used as an intra-lesional steroid injection to treat keloid and hypertrophic scars.
According to Chang et al (2014), "Triamcinolone acetonide (TA) is classified as glucocorticoid S9 in the 2014 List of Forbidden Affairs published by the World Anti-Doping Agency, which causes it to be prohibited in competition when administered orally, intravenously, intramuscularly or rectally".
Maps Triamcinolone
Form
Different triamcinolone derivatives are available, including acetonide, benetonide, furetonide, hexacetonide and diacetate.
Triamcinolone acetonide is a stronger type of triamcinolone, about eight times more effective than prednisone.
Side effects
Side effects of triamcinolone include sore throat, nosebleeds, increased cough, headache, and runny nose. White patches in the throat or nose show serious side effects. Symptoms of an allergic reaction include rash, itching, swelling, severe dizziness, difficulty in breathing. The additional side effect for women is the prolonged menstrual cycle.
A 2018 study found that intra-articular triamcinolone was associated with increased intraocular pressure, which - if persisting for long periods of time or increased acutely enough - could result in permanent loss of vision.
Chemistry
Triamcinolone is an artificial crystalline corticosteroid and a derivative of cortisol (hydrocortisone) and also known as 1-dehydro-9? -fluoro-16? -hydroxihydrocortisone or 9? -fluoro-16? - hydroxyprednisolone and 9? -fluoro-11 ?, 16 ?, 17 ?, 21-tetrahydroxypregna-1,4-diene-3,20-dione .
Society and culture
Brand name
Trade names for triamcinolone include Aristocort (Sandoz, now Novartis), Kenacort (Bristol-Myers Squibb), Kenalog (Bristol-Myers Squibb), Tricort (Cadila), Triaderm (Schering-Plow), Azmacort (KOS), Trilone, Volon A , Tristoek, Tricortone, Ratio-Triacomb, and Trianex.
See also
- Glucocorticoid (a graph comparing various glucocorticoids)
- Triamcinolone acetonide
References
External links
- Triamcinolone Topical | MedlinePlus
- Triamcinolone (Topical Application Route) | MayoClinic
Source of the article : Wikipedia
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