Triamcinolone is an intermediate-acting synthetic glucocorticoid given orally, by injection, by inhalation, or as a topical ointment or cream.
Video Triamcinolone
Uses
Triamcinolone is used to treat a number of different medical conditions, such as eczema, Lichen sclerosus, psoriasis, arthritis, allergies, ulcerative colitis, lupus, sympathetic ophthalmia, temporal arteritis, uveitis, ocular inflammation, Urushiol-induced contact dermatitis, aphthous ulcers (usually as triamcinolone acetonide), visualization during vitrectomy and the prevention of asthma attacks. It will not treat an asthma attack once it has already begun. It has also been used off-label for macular degeneration.
Prior to 2007 it was sold under the name Azmacort as a corticosteroid inhaler for asthma long-term care.
In 2010, TEVA and Perrigo launched the first generic inhalable triamcinolone.
Triamcinolone is used to alleviate infection-induced eczema in fungal skin infections in the combination drug of econazole/triamcinolone.
The derivative triamcinolone acetonide is one of the ingredients of Ledermix, an endodontic (tooth's root canal) lotion used between sessions, and Sanofi sold it under the brand name Nasacort. Triamcinolone acetonide is also used as intra lesional steroid injection to treat keloids and hypertrophic scars.
According to Chang et al (2014), "Triamcinolone acetonide (TA) is classified as an S9 glucocorticoid in the 2014 Prohibited List published by the World Anti-Doping Agency, which caused it to be prohibited in-competition when administered orally, intravenously, intramuscularly or rectally".
Maps Triamcinolone
Forms
Different triamcinolone derivatives are available, including acetonide, benetonide, furetonide, hexacetonide and diacetate.
Triamcinolone acetonide is a more potent type of triamcinolone, being about eight times as effective as prednisone.
Side effects
Side effects of triamcinolone include sore throat, nosebleeds, increased coughing, headache, and runny nose. White patches in the throat or nose indicate a serious side effect. Symptoms of an allergic reaction include rash, itch, swelling, severe dizziness, trouble breathing. An additional side effect for women is a prolonged menstrual cycle.
Chemistry
Triamcinolone is a synthetic pregnane corticosteroid and derivative of cortisol (hydrocortisone) and is also known as 1-dehydro-9?-fluoro-16?-hydroxyhydrocortisone or 9?-fluoro-16?-hydroxyprednisolone as well as 9?-fluoro-11?,16?,17?,21-tetrahydroxypregna-1,4-diene-3,20-dione.
Society and culture
Brand names
Trade names for triamcinolone include Aristocort (Sandoz, now Novartis), Kenacort (Bristol-Myers Squibb), Kenalog (Bristol-Myers Squibb), Tricort (Cadila), Triaderm (Schering-Plough), Azmacort (KOS), Trilone, Volon A, Tristoject, Tricortone, Ratio-Triacomb, and Trianex.
See also
- Glucocorticoid (a chart comparing various glucocorticoids)
- Triamcinolone acetonide
References
External links
- Triamcinolone Topical | MedlinePlus
- Triamcinolone (Topical Application Route) | MayoClinic
Source of the article : Wikipedia
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